After his high school graduation, Yuuki Wakura realizes it has been five years since his sister's disappearance during a "Mato disaster." Throughout Japan, mysterious entrances have opened to a dimension called "Mato"—a demonic metropolis filled with disastrous monsters known as the "Shuuki" that threaten the safety of humans. However, a new hope arose, as the discovery of a Mato fruit that grants supernatural abilities exclusively to women allowed them to fight against the Shuuki. Due to this, a new matriarchal government was formed, establishing a female organization called the Anti-Demon Corps, which caused men to fall to the bottom of society. When Yuuki suddenly finds himself in Mato, he is unable to escape on his own. But just as he anticipates a gruesome end by the Shuuki, a girl in a militia outfit appears and protects him. As the chief of the Seventh Unit of the Anti-Demon Corps, Kyouka Uzen is ambitious yet devalued by her own peers due to her power being deemed unusual. Now in a life-or-death situation, Kyouka takes the opportunity to find out the true potential of her superpower by using Yuuki: in order to defeat the Shuuki, he has to become her slave.

After an eventful winter break, Kyoutarou Ichikawa and Anna Yamada reunite with a stronger bond. They continue to grow in their own ways, with Yamada taking on more challenging photoshoots and Ichikawa maturing both physically and emotionally as he tackles his affections for Yamada. However, spending time together outside of school allows for their relationship to deepen, and it becomes increasingly difficult to deny their budding romantic feelings. Grappling with these unexpected and new emotions, Ichikawa and Yamada realize that, with the passage of time, their relationship is bound to change—and they must ultimately decide whether they wish to remain close friends or finally become a couple.

Expert gamer Tomozaki Fumiya doesn’t exactly fit in, but he wishes he did. With no written rules for success and gameplay that doesn’t work in his favor, the real world seems impossible for someone like him. But, like any noob, all he really needs are some strategies and a seasoned player like Aoi Hinami to help him. Hopefully with her guidance, Tomozaki will gain the experience he needs.

At True Cross Academy, Rin Okumura unknowingly comes across the first signs that something is amiss; ordinary people have been gaining the ability to perceive the invisible creatures that roam the human realm, Assiah. While Rin sees this as an opportunity to make a new friend, his twin brother, Yukio, is more burdened than ever. Swamped with his education, exorcist duties, and teaching position, Yukio has remained silent about his awakened powers, unable to understand their scale or significance. While Rin and his friends prepare for the annual Exorcist Certification Exam, the True Cross Order has uncovered the first artificial gate to the demonic realm of Gehenna. Witnessing its size and the advanced technology that made it possible, the exorcists realize they are now dealing with the Illuminati, an extremely wealthy and powerful organization. Moreover, the inscrutable Illuminati have planted three spies in the True Cross Order—and one may be hiding among the aspiring exorcists sworn to protect mankind from the demonic threat.