Three weeks after the incident that left Captain Napolipolita's ship balancing on top of Graviton City, A-Ko and the gang go on summer vacation. While A-Ko ponders losing some weight and B-Ko devises another plan to defeat her redheaded rival to win C-Ko, Napolipolita and Spy-D experience severe homesickness - begging for a way to return to their home planet. Meanwhile, Hikari Daitokuji - B-Ko's father and the CEO of the Daitokuji Financial Group - arms the local military with new mecha to attack Napolipolita's ship and obtain its advanced technology.

Sixteen years after its destruction by a meteor, Graviton City has been rebuilt into a futuristic metropolis. However, this is of little concern to superpowered high school student Eiko Magami, who only cares about her best friend Shiiko Kotobuki and arriving at school on time. Unfortunately, the incredibly intelligent Biko Daitokuji intends to befriend Shiiko, taking Eiko's place as the Shiiko's best friend using any means she can. Biko decides that, to accomplish this, she must defeat Eiko in combat. In order to overcome her super strength and speed, Biko creates a mecha and challenges Eiko in front of their school gate. As the two commence their battle, an extremely large spaceship hovers over Earth, searching for something left behind.

The Galaxy Federation Police (GFP) desperately wants to cover-up its personnel shortage with new mechanized power-suits. Suzuo, 19-years old, desperately needs a job. Tampopo needs an earthling to fit the prototype of her company's suit and declares Suzuo the perfect candidate! Strong competitors and the wacky A-class criminals fight against our hero in diapers, but they must not recognize each other out of costume or the test results will be a failure- but it's OK if they all live in the same apartment building to save money, right?

An anime adaptation of the 4-panel strip manga release: Nyoron Churuya-san. Based on Suzumiya Haruhi's energetic and 'always up to go' character, Tsuruya. Churuya is a girl with a strong passion for smoked cheese. But Kyon and the rest of the crew know this, and they make use of the weakness. They make her do all kinds of things with smoked cheese as a possible reward. But Churuya isn't aware of this evil plot, thus she maintains the effort for the sake of cheese. Each day is a struggle to get the beloved smoked cheese, but it's much harder than she could ever imagine!