When Fujiko acquires and memorizes papers called the Columbus Files, she is attacked and loses her memory. Lupin, a treasure hunter named Rosaria, and the cackling villain Nazaroff all pursue Fujiko, as she is the only key to the location of Columbus' Egg, a treasure connected to the mysterious Orgone Energy. 

(Source: ANN)

Lupin & co. compete with a greedy bank president and her goons to solve the mystery leading to a broach, a treasure said to be behind the success of history's most powerful rulers. 

(Source: ANN)

Jigen tells the story of the gang's first meeting. Jigen, still a member of the Mafia, is hired to protect an ancient artifact - one that Lupin and Fujiko are both trying to steal. Meanwhile, Inspector Zenigata, then of the Japanese police force, has come to the U.S. on Fujiko's trail, and Ishikawa Goemon is searching for the lost treasure of his clan. 

(Source: ANN)

Zenigata arrives on the ship "Machine Gun Kelly", a casino on the water owned by the mafia, because Lupin plans on stealing the casino's money. Lupin and his gang manages to break into the ship's vault but was unable to escape with the money due to Zenigata's shooting. However, there was another purpose the ship had, one that Lupin was aware of; to search for a sunken ship filled with gold. Lupin managed to steal this data while he was on the ship, however, now they have to contend with Zenigata, the mafia, and a secret organization whose base is under Alcatraz, as they attempt to uncover the secret behind the organization and the sunken treasure.

(Source: ANN)