The fourth season of FLCL, and sequel to FLCL Alternative. It centers on three teenagers who graduated and have started working. The CGI anime will have a theme of the feeling of being an adult.

Ayakashi are strange, supernatural creatures invisible to the majority of people. Though most are harmless, some ayakashi attack humans to devour their life force. Exorcist ninjas are tasked with protecting people from these spiteful spirits. Matsuri Kazamaki is a young exorcist ninja born to a prestigious clan. His childhood friend, Suzu Kanade, is an ayakashi medium—an individual with immense vitality that attracts ayakashi. Matsuri deems all ayakashi threatening and wishes to keep Suzu as far from them as possible, but this clashes with her desire to remain close to them. One day, the pair encounters Shirogane, the "King of Ayakashi," who is hellbent on consuming Suzu. As she is about to be eaten, Matsuri comes to the rescue and manages to seal the ayakashi's powers—but not before Shirogane takes revenge by turning him into a girl! Until he finds a way to transform back, Matsuri must adjust to his new, peculiar lifestyle while fighting against hostile ayakashi. Moreover, Suzu is now conflicted about her feelings toward Matsuri—further plunging their relationship into a state of ambiguity.

Dwelling in the small outskirts of a peaceful town, Lawrence works as a local pastor for the townsfolk. When in need, he is responsible for guiding people to the church to visit the "Saint"—a symbol of good morals who heeds each parishioner's struggles and grants them sincere advice. Cecilia, a kind young girl, is tasked to fulfill this role; however, this tiresome job quickly exhausts her. That, paired with her hidden somnolent nature, often causes her to laze around the church. This leaves Lawrence to care for the church all by himself. While Cecilia sleeps in anticipation for her next visitor, Lawrence caters to her needs alongside performing the church's numerous responsibilities. Slowly but surely, they begin to form a comfortable and trusting friendship with one another. Lawrence accepting Cecilia's lax nature elates her while she grows accustomed to Lawrence's overly-doting nature. However, as the adoring and absent-minded saint's feelings for the dense and overly protective pastor progress past friendship, how will he respond?

Five years after the events of Dragon Ball, martial arts expert Goku is now a grown man married to his wife Chi-Chi, with a four-year old son named Gohan. While attending a reunion on Turtle Island with his old friends Master Roshi, Krillin, Bulma and others, the festivities are interrupted when a humanoid alien named Raditz not only reveals the truth behind Gokuu's past, but kidnaps Gohan as well. With Raditz displaying power beyond anything Goku has seen before, he is forced to team up with his old nemesis, Piccolo, in order to rescue his son. But when Goku and Piccolo reveal the secret of the seven mystical wish-granting Dragon Balls to Raditz, he informs the duo that there is more of his race, the Saiyans, and they won’t pass up an opportunity to seize the power of the Dragon Balls for themselves. These events begin the saga of Dragon Ball Kai, a story that finds Goku and his friends and family constantly defending the galaxy from increasingly more powerful threats. Bizarre, comical, heartwarming and threatening characters come together in a series of battles that push the powers and abilities of Goku and his friends beyond anything they have ever experienced.