The story is set in Aquafall, a fantasy world abound with water and greenery, and populated by dragons and fairies. Meteorites suddenly bring forth evil creatures that threaten all living things on the planet. The fairy Syrup assembles the Aquafall Defense Force, with three girls of the dragon clans as recruits. The story follows Syrup and the dragon girls Leviathan, Bahamut, and Jörmungandr as they work together to battle enemies and grow up.

Yuu, Persia, Mai and Yumi are together in a science fiction-like adventure. An awful monster assault young and beautiful girls, leaving them transformed into ugly hags: only our four magical girls with their powers can fly to the space and fight for Earth 's sake, so Yuu transforms into Creamy Mami, Mai into Magical Emi, Persia into Fairy and little Yumi draws space suits for all of them.

Miura Kyoji, a dedicated kendo student, discovers that his shisho (master) Tate Masanari is a reincarnated Incan warrior named Yawaru who wishes to destroy the world to purify it. Kyoji himself is the warrior Bilka, who foiled Yawaru's plans in their previous lives. Yawaru gathers other awakened spirits to release the powers of nature. Now Kyoji must wrestle with his own fate and decide if he is merely a vessel for the reincarnated soul or if he is truly Miura Kyoji and which will be better able to save the world and the future as he knows it.