At Fólkvangr, a front constructed inside an asteroid, the Gundam Lfrith is undergoing operating tests in the Vanadis Institute's laboratory. The Lfrith has not yet managed to meet the conditions imposed by the council, and test pilot Elnora Samaya is growing impatient. That same day, her daughter is celebrating her fourth birthday...

Suletta Mercury leaves her planet and enters the Asticassia School of Technology at the behest of her mother. There, right and wrong are determined through duels between students, and the top-ranking duelist will receive Miorine Rembran as their fiancée—this prize being decided by Miorine's father. When Guel Jeturk, the best pilot in school and Miorine's current fiancé, demands that his betrothed move in with him, Suletta disapproves, so Guel challenges her. Although she emerges as champion, Suletta is subsequently detained on suspicion of piloting a forbidden type of mobile suit—a GUND-ARM, or "Gundam"—which results in her victory being voided. Miorine refuses to accept any more injustices and proposes another duel with even higher stakes. Now, Suletta must triumph a second time, otherwise she will be expelled and the Gundam Aerial that means so much to her will be destroyed.

Sometime in the distant future, mankind is forced to live in domed cities while the rest of the world is left to recover from years of environmental hardships. In the Siberian Dome-polis, professional gamer Gainer Sanga and mercenary Gain Bijou commandeer an Overman and lead a mass exodus out of the city.

In 2059, five decades after the Space War I conflict seen in the first Macross story. Macross Frontier, the 25th New Macross Class super-long-distance colonization fleet, is journeying through the galaxy to a new paradise to call home. However, it is locked in a state of war with a strange enemy called Vajra. Macross FB7 is the 30th anniversary work of the Macross franchise.