The fourth season of FLCL, and sequel to FLCL Alternative. It centers on three teenagers who graduated and have started working. The CGI anime will have a theme of the feeling of being an adult.

-ADVERTISEMENT- The year is 2242. Humanity was forced to seek refuge deep underground due to the unprecedented calamity known as the "Tears of the New Moon," but following the collapse of the underground city-state of "Amasia," they begun to venture back towards the surface with hope of living there once more. Forming settlements called "Nests" scattered across the surface, adventurers known as "Drifters" continues to battle the lingering threat of the "Enders" and mine the "AO Crystals" which are an essential energy resource necessary for the operation of the nests. In the nest "Rock Town" where such Drifters gather, one wishing to become such a Drifter one day, "Kanata," alongside the skilled Drifter "Tokio," went to explore the ruins of an old museum where Kanata happens to discover a very beautiful sleeping "Magus." With the encounter of the mysterious Magus "Noir," a tale of destiny is slowly beginning to unfold.

This science fiction omnibus depicting a doctor who "treats" robot and humanoid problems takes place in the near future, when humanoids with artificial intelligence account for 10% of the population. The main character, Dr. Sudo Hikaru, also has the undercover name Moggadeet, under which he secretly takes on illegal medical procedures. For example, for a man who inadvertently infected his humanoid wife with a computer virus when illegally backing up her data, Sudo proposes an operation to rewrite her memory using backup data. Could an existence replaced by backup data truly be said to be the same as it was before?

Now in possession of the Edens Zero, Shiki Granbell has gathered the Four Shining Stars. With the help of his new friends, Shiki will be able to breach Dragonfall—the border of the Sakura Cosmos swarming with mechanical dragons. Once that is achieved, he can continue his quest to find the goddess Mother. Before the Edens Zero crew can advance their journey, they notice a mysterious warship following them. Upon learning that the ship—the Belial Gore—belongs to Drakken Joe, Shiki and his crew attempt to infiltrate it, intent on figuring out why the Dark Alchemist is after them. In the process, the Edens Zero is taken hostage by Drakken's subordinates. Though they are in a tight situation, Shiki refuses to back down. Working together with his friends, Shiki will have to take down the Dark Alchemist if he hopes to make it out of the Belial Gore alive.