Mankind has traveled to the stars and come across various alien civilizations, now long dead. Upon discovering the archaeological remains of such a civilization on the planet Solo, humanity finally has its first encounter with a living alien species: the Buff Clan. When Karala Ajiba, the daughter of the Buff Clan's military leader, sets foot on the surface of Solo, the Buff Clan launches a brutal assault on the colony to retrieve her. In order to escape, Cosmo Yuki, Kasha Imhof, and Bes Jordan climb aboard three trucks, which soon transform into the giant humanoid robot Ideon. When the settlement on Solo is destroyed, the survivors board a recently discovered spaceship—the Solo Ship—and flee, endeavoring to get away from the aliens and finally find peace. The relentless Buff Clan, however, is still in hot pursuit and will not give up so easily. [Written by MAL Rewrite]

In the year 2199, Earth faces its greatest crisis. Due to unrelenting bombings by the alien race known as "Gamilas," the planet can no longer sustain its inhabitants. In exactly one year, humanity is set to become extinct. In desperation, the people of Earth establish the Earth Defense Force, their last defense against the power-hungry Gamilas Empire. However, humanity finds a glimmer of hope after receiving a message from the mysterious planet Iscandar, which offers them a device that would restore Earth to its former glory. With salvation in sight, the Earth Defense Force calls on the prolific Space Battleship Yamato and swiftly assembles a crew to make the 168,000 light-year trek to Iscandar and receive their aid. Among the crew are young officers Susumu Kodai and Daisuke Shima, along with several other newly promoted leaders, all under the command of the distinguished Captain Juuzou Okita. Forced to learn how to handle the ship's innovative technology while dealing with the onslaught of Gamilas fleets, the inexperienced cast of Uchuu Senkan Yamato 2199 must summon every inch of their resolve to survive the many hardships aboard the Yamato and complete their mission: to save humanity before it's too late. [Written by MAL Rewrite]

A stray missile from a confrontation between the Galman empire and the Bolar Federation crashes into the sun, turning it into a time bomb of radiation. The Star Force once again sets off into space, this time on a quest to look for a new world for the human race. (Source: ANN)

A year has passed since the Star Force returned to save the Earth but another danger now approaches from deep space. A gigantic White Comet hurtles toward our galaxy, obliterating everything in its path. But it is no ordinary comet—it is the deadly Comet Empire, conqueror of worlds... and Earth is the next target! Against orders, the Star Force blasts off to investigate, but even if they can get past the flagship Andromeda, they don't yet know the true nature of their new enemy! (Source: AniDB)