After escaping a bus hijacking with the help of masked superhero Strange Juice, Yuuta Iridatsu finds his soul separated from his body and in the care of a perverse cat spirit, Chiranosuke. As a spirit, Yuuta wanders around his residence, the Korai House, aiming to regain his body and observe the other residents: Meika Daihatsu, a genius inventor; Mikatan Narugino, a cheerful idol; Ito Hikiotani, a shut-in NEET; and Rabura Chichibu, a spiritual medium. After catching a glimpse of Narugino's undergarments, Chiranosuke reveals to Yuuta that he becomes exponentially stronger upon seeing panties. However, if he sees another pair while he is still a spirit, his power will cause an asteroid to crash into the earth, ending the world and killing his friends. Punch Line follows Yuuta as he unravels the mysteries surrounding Korai House, its residents, and a villainous organization attempting to end the world. Will Yuuta be able to save everyone, or will the ever-present threat of panties result in their doom? [Written by MAL Rewrite]

Based on the American cartoon, "The Powerpuff Girls." Professor Utonium and his son Ken are studying the strange Chemical X. When a mochi cake falls into the formula, it changes into Chemical Z. Ken fires a ray of Chemical Z at a glacier in Tokyo Bay, however that causes strange black and white lights to scatter. The black lights turn its victims into monsters, with emphasis on a black light hitting a zoo monkey and transforming him into Mojo Jojo. The white lights, however, aim at three normal girls, Momoko, Miyako, and Kaoru. This gives them the power to transform into superheroes, the Powerpuff Girls Z!

A boy gets involved in an accident when in kindergarten, horribly damaging his arm, but the doctors somehow manage to save it. Now, several years later, his arm seems to be becoming the focus of strange events as it turns out to be more than a normal arm. Meanwhile, a secret organizations is out to get hold of him and the power he possess.

The 2nd Chapter continues the story of Ryo Takatsuki and his companions' quest to discover the secret of the mysterious A.R.M.S. they all possess and what the future may hold for them. They now know where the answers lie but to get to them, they must fight a desperate fight of survival against a powerful military corporation that wants their secrets no matter what the cost. (Source: AniDB)