Kusuo Saiki is a high school student who possesses a wide range of psychic abilities. While many may believe these abilities to be a gift, to Kusuo, they are a curse as he must fight strange odds in order to try to live a normal life. Forced to use his psychic powers to protect his secret or to make up for his father's incompetence at work, will Saiki eventually come to realize how his powers can actually help his friends and family? [Written by MAL Rewrite]

In Stern Bild City, those with special abilities are called "NEXT," and can use their powers for good or bad. A unique organized group of NEXT appear regularly on Hero TV, where they chase down evildoers to bring limelight to their sponsors and earn Hero Points in the hopes of becoming the next "King of Heroes." Kotetsu T. Kaburagi, known as "Wild Tiger," is a veteran hero whose performance has been dwindling as of late, partially due to his inability to cooperate with other heroes. After a disappointing season in which most of the other heroes far outperformed Tiger, he is paired up with a brand new hero who identifies himself by his real name—Barnaby Brooks Jr. Barnaby, nicknamed "Bunny" by his frivolous new partner, quickly makes it clear that the two could not be more different. Though they mix as well as oil and water, Tiger and Bunny must learn to work together, both for the sake of their careers and to face the looming threats within Stern Bild. [Written by MAL Rewrite]

High schooler Ganta Nakami has trouble falling asleep most nights. As a result, he is irritable at school, always searching for an opportunity to find a secluded place to doze off. On the other hand, Isaki Magari is a free spirit who is well liked by her friends, but no one is aware of her sleep disorder. She makes use of the school's abandoned astronomy club observatory as her secret sleeping bunker when she needs to get some shut-eye. As fate would have it, Nakami finds Magari napping in the observatory. When Magari discovers that she and Nakami have something in common, she offers to share her secret sleeping spot with her fellow insomniac. As the two find warmth in each other's company, the struggles they face start to become easier to confront.

After years of conflict, humans and monsters have settled their differences and are now at peace. This post-war era led to the foundation of Lindworm—a town which has since become the focal point of racial harmony. As a human doctor specializing in monster biology, Glenn Litbeit runs a small clinic alongside his partner, Saphentite Neikes, who is a half-snake monster known as a lamia. He uses his knowledge to tend to any monsters who seek his aid. Whatever affliction, concern, or injury it may be, he will always be there, ready to help. [Written by MAL Rewrite]