Junior high school student Kimichika Haijima moves back to his hometown, Fukui, after causing trouble in the Tokyo Junior High School volleyball club. There, he is reunited with his childhood friend, Yuni Kuroba, who possesses outstanding physical abilities, but is vulnerable under pressure. Haijima, with his overwhelming passion and talent for volleyball, forms an ace combination with Kuroba. The two enroll at Seiin High School, where they join the volleyball club. Awaiting them are the 163 cm hot-blooded captain Shinichirou Oda, the talented and sharp-tongued vice-captain Misao Aoki and his third-year pair, and second-year students, including Akito Kanno, who is always wearing long sleeves due to his allergy to sunlight. The newborn team breaks its former shell of weakness and becomes Fukui's rising star. This is a certain team's journey to victory, with a series of fascinating rivals standing in their way.

Three months have passed since the Demon King was defeated by a hero. Mankind rejoices over their victory, but dwellers of the demon world do not share the same sentiment. With the loss of their king, they must now hold a tournament to decide who will become his successor. Monitoring the competition is the hot-headed yet powerful Vamirio—one of the Four Heavenly Kings. Among all the participants, she is extremely distrustful of one: Helck, a human hero who claims to hate humanity. As much as she wants to get rid of him, it is impossible due to Helck's incredible strength and popularity. Amidst the competition, Vamirio discovers that humans have vanished from various towns. As a result of this puzzling turn of events, Vamirio grows desperate to reveal Helck's true intentions by carefully crafting a plan to make Helck lose. If she proves to be successful, she might uncover where his loyalty truly lies before the demon world is endangered.

In the great city of Metropolis, severe community structures and prejudice dominate a world where humans and robots live together. Unrest and violence increase with each new day. Searching for the scientist Dr. Laughton, suspected to violate human rights by trading organs, the Japanese detective Shunsaku Ban and his nephew Kenichi arrive at Metropolis. In the scientist's laboratory, Kenichi discovers a girl without any memory of her past life. He decides to help her, so they run away together. His uncle follows him and penetrates the dark secrets of the city to find Duke Red, the man ruling from the shadows. Meanwhile, Kenichi desperately tries to protect the mysterious girl from the people hunting her. However, Duke Red and his adoptive son have their own deep reasons for chasing the girl. These reasons are connected to her true identity and the struggle for the domination of Metropolis...

After Jinta and Suzune ran away from their home as children, they were taken in by Motoharu—the virtuous sentinel of Kadono Village—and his daughter, Shirayuki. The settlement was ruled by its shrine maiden, Itsukihime, whom only a select few were allowed to interact with. When Itsukihime passed away, Shirayuki was appointed in her place. Wishing to stay in contact with her, Jinta worked diligently for years and was finally selected as the next sentinel. As the protector of the village, Jinta's duty is to eliminate any threats. One day, he encounters a demon in a nearby forest. At the end of the battle, the demon makes a proclamation about the destined ruler of all demonkind. He attaches his severed arm to Jinta, turning him into an unaging demon man. By the time Jinta comes to, Kadono is on fire. Suzune has transformed into the demon from the divination, and due to a series of misunderstandings, she murders Shirayuki and flees. Devastated, Jinta cannot forgive Suzune for her actions; he departs on a journey to find her. As Jinta travels around Japan across the eras, he endeavors to protect as many people as possible from aggressive demons. In his quiet moments, he contemplates what he should do when he once again faces his childhood friend.