Since reincarnating into a new world, Ryouma Takebayashi has used his god-given graces to tame countless slimes and employ them to improve the lives of everyone around him. With the astonishing success of his laundry shop, Bamboo Forest, he is finally ready to take on new frontiers and open a branch in the neighboring city of Lenaf. Abiding by his promise with his dearest friend, Eliaria Jamil, Ryouma makes every day count, whether learning new techniques, forming connections, or even discovering more species of slime.

Unable to achieve the desired results on the first and second days of the Inter-High competition, members of the Souhoku High Bicycle Racing Club use their frustration as motivation to perform better on the final day of the race. However, it is easier said than done as they are up against the overwhelming talent of Hakone Academy and the shrewd strategies of Kyoto Fushimi High. Despite the challenge, Souhoku members are not disheartened by the obstacles that they need to overcome. After all, no matter what their opponents try, Souhoku will have the last laugh as long as they are the first to cross the finish line.

Mitsuha Yamano could not have had it worse. After failing to enter her university of choice and losing her entire family in an accident, she finds herself plummeting off a cliff due to an especially fragile guardrail. Through what seems to be the only bit of the fortune left in her life, Mitsuha's firm unwillingness to die allows her to be transported to another world, where she ends up surviving. In this foreign land, Mitsuha wanders around for days before collapsing from exhaustion and being rescued by a little girl named Colette. Not long after, she finds herself in yet another life-threatening situation, and her indomitable will shines once more, granting her an audience with a divine cosmic being. The entity reveals to Mitsuha that she has acquired not only superhuman regeneration but also the ability to transport between worlds at will. Armed with this new information, Mitsuha brainstorms ways to utilize her newfound power to its full potential. Realizing that she can take goods from Earth and resell them to the other world at a higher price, she resolves to save up eighty thousand gold coins to be able to retire comfortably.

Following the successful end of the Fourth Shinobi World War, Konohagakure has been enjoying a period of peace, prosperity, and extraordinary technological advancement. This is all due to the efforts of the Allied Shinobi Forces and the village's Seventh Hokage, Naruto Uzumaki. Now resembling a modern metropolis, Konohagakure has changed, particularly the life of a shinobi. Under the watchful eye of Naruto and his old comrades, a new generation of shinobi has stepped up to learn the ways of the ninja. Boruto Uzumaki is often the center of attention as the son of the Seventh Hokage. Despite having inherited Naruto's boisterous and stubborn demeanor, Boruto is considered a prodigy and is able to unleash his potential with the help of supportive friends and family. Unfortunately, this has only worsened his arrogance and his desire to surpass Naruto which, along with his father's busy lifestyle, has strained their relationship. However, a sinister force brewing within the village may threaten Boruto's carefree life. New friends and familiar faces join Boruto as a new story begins in Boruto: Naruto Next Generations.