Ungrar, the King of Viruses, has escaped from his prison cell in Vaccine World. Maya, the Goddess of Vaccine World sends Mugimaru down to Earth to find a human to accept the powers of Vaccine World and become the Magical Nurse. He finds the best (and the only willing) person for the job when he meets Komugi Nakahara. Komugi is a playful, lazy, and easily distracted (typical) teenager whose dream is to become a cosplay idol. Balancing her career with the Kiri-Pro Promotion Company and her new job battling Ungrar's loyal henchman, the Magical Maid Koyori, Komugi delights audiences in this parody anime series.

The Angelic Guard, who call the heavens their home, have been tasked with collecting the orbs scattered across the world. Lucifer—a leader of the Angelic Guard with a rebellious streak, said to wield power rivaling the Almighty—carries out her duty along with Uriel, also a leader of the guard. Together, they go about executing their mission, until Holy Magistrate Keter—the one who leads the heavens under the Almighty's will—tells Uriel of Lucifer's planned rebellion. Initially in disbelief, Uriel then learns that the accusations against Lucifer may be connected to an event that once threatened to shatter the heavens.

Mysteria Academy is a prestigious magic school that teaches magic without discrimination to the three factions (men, gods, demons), who usually are engaged in battle with each other. Two of the academy's students are Anne, a princess and honor student, and Grea, a princess born from a dragon and a human. (Source: ANN)

Falling in love at first sight with a collapsible bicycle outside the station, Ami Kurata, first-year university student empties her account without a second thought and buys the bicycle. Now she enjoys weekend cycling trips with Aoi, her childhood friend, and Hinako, a senior at her university. "Owning a road bike may change your view of the world completely." Prompted by the comment, Ami purchased a road bike, and she is really impressed with the traveling performance. As soon as she places her feet on the pedals and presses down, everything about riding a road bicycle—the lightness of the pedal, the speed, the acceleration—is nothing like she has ever experienced. Ami's cycle life gets going with the new road cycle as her partner! (Source: Showgate, edited)