Black Jack is an "unregistered" doctor with a clouded, mysterious past. He works with his little assistant Pinoko (who has a massive crush on the doctor), dealing with medical cases not very well known, which can be strange, dangerous, or not known at all. But he is a genius, and can save almost any of his patients' life (as long as they have the money for it, that is), and is known to many around the world, especially to those of medicine and science. He's a man of science himself, and does not believe much until he has seen it, yet it is many times he is surprised by love and nature often overpowering the science he bases his life in.

"Unwritten" - An episode about Futaba and Kou in middle school. Based on the chapter called "Unwritten." also known as chapter 0 or Prologue. "Page.13" - An episode that continues the story after the television series's 12th and final episode. (Source: sakisaka10)

Yako Katsuragi is an acclaimed high school detective, who, despite her young age, has solved many cases. In fact, there seems to be no case that she can't solve, or any culprit that escapes justice. But within the walls of her detective agency lies the secret to her prolific crime-solving skills: the cases are actually solved by her assistant, Neuro Nougami. However, to call Neuro an ordinary man would be incorrect. In reality, he is a demon, who came to the human world in search of the ultimate mystery, having already solved every mystery in the demon world. With Yako as his proxy, he feasts on the negative energy released by humans when they commit crimes. Thus, he promises to help Yako solve the mystery of her father's death. But to do so, he must avoid drawing too much attention to himself, which is why Yako plays the role of the detective. Majin Tantei Nougami Neuro follows this unlikely duo as they solve case after case to satisfy Neuro's ravenous appetite and Yako's desperate search for the truth of her father's death.

There is a small village called Jimuna on the continent of Jamu Jamu. This village is home to a girl named Kukuri. She is the last descendant of the Migu Migu Tribe. She is raised by an old witch who teaches her the secret magic of the tribe, but Kukuri is not a good student. In the same village lives a boy named Nike. He has been raised by very strict parents. They discipline their son to become a brave hero of the village. Nike himself does not want to be a hero at all, but he grows up to become a mighty boy. One day the king of the village, Kodai, recruits troops to fight against the ruler of the darkness, Giri. Kukuri and Nike are accepted. The two children, the strong but reluctant hero Nike, and the eager but unskilled little witch Kukuri, set out on a wonderful journey full of adventures and friendship. (Source: Nippon Animation)