After a slow but eventful summer vacation, Shuchiin Academy's second term is now starting in full force. As August transitions into September, Miyuki Shirogane's birthday looms ever closer, leaving Kaguya Shinomiya in a serious predicament as to how to celebrate it. Furthermore, the tenure of the school's 67th student council is coming to an end. Due to the council members being in different classes, the only time Kaguya and Miyuki have to be together will soon disappear, putting all of their cunning plans at risk. A long and difficult election that will decide the fate of the new student council awaits, as multiple challengers fight for the coveted title of president.

At the renowned Shuchiin Academy, Miyuki Shirogane and Kaguya Shinomiya are the student body's top representatives. Ranked the top student in the nation and respected by peers and mentors alike, Miyuki serves as the student council president. Alongside him, the vice president Kaguya—eldest daughter of the wealthy Shinomiya family—excels in every field imaginable. They are the envy of the entire student body, regarded as the perfect couple. However, despite both having already developed feelings for the other, neither are willing to admit them. The first to confess loses, will be looked down upon, and will be considered the lesser. With their honor and pride at stake, Miyuki and Kaguya are both equally determined to be the one to emerge victorious on the battlefield of love!

On her way home from school, Yukari Hayasaka is approached by a weird-looking guy who starts looking at her body intently. He's got blond spiky hair, a spiked choker, and multiple piercings on his ears and face. She wants nothing to do with him, and runs away, only to bump into a very tall and beautiful purple-haired woman with a flower pattern around her eye. Yukari faints from shock and wakes up later in a strange place called the Atelier. It turns out that these strangers are fashion designers who attend the most famous art school around, Yazawa Art Academy, and their group wants Yukari to model for their brand in Yazawa Academy's upcoming show. Yukari turns down their offer and escapes the Atelier, but unknowingly leaves her school ID behind. George Koizumi, the head designer, later sees it and immediately knows she would be the perfect model for them and will not stop until he gets what he wants—and he wants her. Yukari had never considered something as frivolous as modeling before, but could life among these eccentric designers actually prove to be fun? Or will Yukari lose herself in this world of art and passion?

Chiyo Sakura is a cheerful high school girl who has fallen head over heels for the oblivious Umetarou Nozaki. Much to Chiyo's confusion, when she confesses to her beloved Nozaki, he hands her an unfamiliar autograph. As it turns out, the stoic teenage boy is actually a respected shoujo mangaka, publishing under the pen name Sakiko Yumeno! A series of misunderstandings leads to Chiyo becoming one of Nozaki's manga assistants. Throughout the hilarious events that ensue, she befriends many of her quirky schoolmates, including her seemingly shameless fellow assistant, Mikoto Mikoshiba, and the "Prince of the School," Yuu Kashima. Gekkan Shoujo Nozaki-kun follows Chiyo as she strives to help Nozaki with his manga and hopes that he will eventually notice her feelings.