The year is 21XX. Reploids are commonplace now, after Dr. Cain rediscovered Dr. Light's old lab and based several designs off of Dr.Light's original, called "Megaman X." X, meanwhile, has joined the Maverick Hunters, and works with unit leader Zero under the command of General Sigma. It is their job to terminate rogue reploids, those who have become violent.

The second part of the new Hokuto no Ken pentalogy. The story of this OVA centers around Yuria.

Sousei no Aquarion Evol is set in the spring of 1966. Shin Tsukishima, who is travelling to get a crystal radio, meets Yuno Kawazu, a girl crying on a beach in Izu. Shin and Yuno are guided by the Book of Genesis and meet each other halfway. The boundaries between three worlds begin to distort. Original episode that will be screened at Project Aquarion's 10th Anniversary event scheduled to be held on June 28, 2015.

Yuno Gasai lives a normal life as a first-year in high school. She gets along well with her parents and even has a small circle of friends. However, she cannot help but feel as if someone is missing from her life, someone so important to her that it was as if she had lived another life trying desperately to stay with them. After a class trip to the beach, Yuno returns home; but in the middle of the night, she receives strange messages from a voice only she can hear. The voice informs her of the person she is desperate to meet and that she must find him. Soon, she finds herself in a mysterious realm, her only goal being reunited with the person she cannot remember. Though obstacles stand in her way, Yuno will stop at nothing to meet her beloved once again.