On a rainy afternoon, a male high school student awakens freezing on the streets with no memory of how he got there. His classmate and crush, Karen Inukai, finds him and takes him back to her home where, to his surprise, she starts to undress. She seems intent on bathing with him, though he has no idea why. When she holds him once more, he catches a glimpse of himself in the mirror—discovering that he has turned into a dog! Inukai adopts the puppy and names him Pochita. Now, he must adjust to life as a dog and figure out how to get out of this strange predicament. But while he mulls over an escape plan, Pochita sees a whole new side to Inukai that he never saw at school.

One day, Hitoyoshi Yokoya wakes up to a mysterious nameless girl dressed as a maid ringing his doorbell, asking to be his servant. With her former master referring her to the Yokoya household, she offers her expertise as an assassin. Intimidated by her background, Hitoyoshi tries to send her away; but when she leaves something behind, he rushes to return it to her and is nearly hit by a truck in the process. With her fast reflexes, the girl saves him just in time, and Hitoyoshi ends up taking her in. Ironically, the maid lacks any skills apart from the art of killing she has perfected since childhood. Nevertheless, Hitoyoshi welcomes the girl with open arms, encouraging her to leave her monochromatic past behind and experience a normal life. To seal the deal, Hitoyoshi names her Yuki, marking the beginning of her path to redemption and happiness.

Allen, a misanthropic wizard, lives deep within the forest. He is known as the "Demon Lord" and feared by those around him. One day, while living his life as a hermit, he comes across a young girl named Charlotte who has collapsed in the forest. Despite being innocent, she was accused of evil deeds, had her engagement annulled, and was forced to flee her country. When he heard that, Allen remembered the agony of being betrayed by a group he once thought was his companions. After hearing the story of the 17-year-old's exploitation, Allen decides, "I'll let her live in my mansion, and I'll teach her all sorts of bad things..."

As she heads off to her entrance ceremony at Sainotama Girls' High School, Akane Kikuchi muses over her grade school dream of becoming a manga artist and the lack of progress that she has made. When she finally arrives at school, she is surprised to learn that she is once again in the same class as her two best friends: the deadpan and emotionless Shiori Saginomiya and the hyperactive and ridiculous Nozomu Tanaka. Tanaka then comes to the obvious realization that she can't achieve her grade school dream of being popular with the boys and getting a boyfriend by going to an all-girls high school. In desperation, she begins asking the girls in her class to introduce her to their guy friends. Her classmates, however, are anything but ordinary. From a grandmother-loving loli to a reclusive chuunibyou to an overly analytical stalker, each one is given a fitting nickname by Tanaka to accentuate their weirdness. And so begin the wasteful days of these high school girls, each day kicked off with a simple question: "Hey, wanna hear something amazing?" [Written by MAL Rewrite]