In his laboratory, biotechnology expert Dr. Kochin gathers the dragon balls intending to free his master Dr. Uirou, a mad scientist hellbent on ruling the world, forever frozen in the never-melting ice of the Tsurumai-Tsuburi Mountains. Attempting to locate the dragon balls, Gohan Son and Oolong arrive at the scene and are ambushed by several creatures known as "Bio-Men." Training nearby, Piccolo attempts to save them but is then attacked by three mysterious warriors. When the ice beneath them breaks, it cuts their altercation short, burying Gohan and Oolong within.

After regaining consciousness, they return home to Kame House only to encounter Bio-Men, demanding Muten-Roushi to follow them. Refusing, he easily defeats the creatures, piquing Dr. Kochin's interest. Under the impression of Muten-Roushi being the strongest man in the world, Dr. Kochin takes Bulma hostage, forcing Roushi's agreement to accompany him in mysterious plans involving his master. Who are Dr. Kochin and Dr. Uirou? What even is their purpose?

[Written by MAL Rewrite]

Fortune Arterial's story revolves around the male protagonist Kohei Hasekura, who transfers into a prestigious public school in the style of an English six-year school encompassing junior-high and high school students. The school is on an island named Tamatsu Island off-shore from mainland Japan, and the only way to get there is by boat. Soon after transferring, he discovers that one of the student in the class next door to his, Sendo Erika, is in fact a type of vampire.

Five hundred years ago, the fantasy world of Alneath was torn apart by a war between magically gifted immortals and mortals armed with magical artifacts. The conflict came to an end when mortals' hero, Gram, slayed the Demon Lord Veltol Velvet Velsvolt. In 2099, the world looks a bit different. Alneath and technologically advanced Earth have fused in an event known as Fantasion. Immortals have been hunted down to near extinction, and technological implants called Familia allow mortals to use magic. As the new world slowly recovers, Veltol's vassal Machina Solege resurrects him in Shinjuku, a techno-magical city constructed in the middle of devastated lands. However, Veltol's magic is severely weakened, and his former ally Marcus has betrayed him. To regain his fame and magical abilities, Veltol follows the advice of Takahashi—Machina's friend and a professional hacker—to start an unusual career: live streaming. His sharp tongue and comically poor gaming skills quickly secure him followers, but to dominate the world once again, Veltol must first uncover Shinjuku's secrets and thwart Marcus' vile plans.

While saving a child from harm, otaku Asahi Ikusaba is transported to another world and believes he has reincarnated with cheat skills similar to those of the characters from his favorite games and novels. Unfortunately, reality strikes when an encounter with a powerful monster shows that he is still nothing more than an average person. In this moment of extreme danger, Asahi instinctively calls out to his overly doting sister, Maya, who appears out of nowhere, possessing the overpowered abilities he thought he had. Maya is ecstatic to see her brother again and resolves to use her newfound powers to protect Asahi no matter what. Together, the close-knit siblings attempt to find a way back home while enjoying their new lives. However, it soon becomes clear that their arrival in this world may have had a purpose. With the Demon King's overwhelmingly powerful army approaching, no one but Maya seems to be able to stand in its way.