The sixth season of Hetalia. Like the previous season, the majority of the episodes adapted one chapter or story from the original source material rather than spreading them out over a number of episodes. Multi-episode storylines include England and America trying to cooperate with one another as they face off against Italy and Germany on the African Front of the Second World War, The Nordic countries showcasing their eccentricities, and Sealand and his friends searching the world to find more micronations to become friends with.

Horiguchi Genki was 5 years old boy. His mother died when he was born, and he was raised only by his father. His father, Shark Horiguchi, was a professional boxer, but he was ruined and become an itinerant boxer. However, Genki believed his father was strong and he would become a champion, and he had a dream to become a strong boxer as his father. After his father’s death, he was adopted by his grandparents. Although they opposed Genki boxing, Genki made up his mind to become a boxer, and he continued training secretly. Meeting with various people, for example, Teacher Ashikiwa who resembles his mother, Mishima who is a high school boxing champion, he made his way to be a boxer.

Yo Hinomura was an ordinary Japanese potter when a run-in with a Chinese mafia changed his life forever. Now an assassin for the 108 Dragons, Yo is the perfect killing machine. As a sign for remorse over his victims, he sheds tears after eliminating his targets. Because of this, he is infamously known by the Dragons and every crime syndicate in the world as "Crying Freeman."

In order to fulfill their dead father's wish, the siblings, Takane Kiku and Takane Ryuji aims for the champopn title of the boxing arena. The sister, Kiku, will act as the trainer while her brother, Ryuji, will concentrate on the role of the boxer and learn the Boomerang. His battle with many rivals has led to the growth and maturity of Ryuji. The junior high boxing tournament has began and Ryuji will be fighting with his arch-rival, Kenzaki Jun. The battle begins.