For as long as the locals can remember, the Champignon Witch, Luna, has lived hidden in her cottage on the outskirts of the kingdom, deep within the Black Forest. Despite her occasional trips into town to deliver medicine, no one dares to come close to her as poisonous mushrooms grow everywhere she goes. Furthermore, as a black witch, Luna must lay low to avoid execution, as the kingdom only acknowledges and accepts white witches. Luna's lonely life turns around when she saves a dying boy named Lize. Upon learning that Lize is destined to become The End of All Things, Luna offers to become his teacher and stray him away from the path of evil. She must overcome her inexperience and create a great magician out of Lize to avoid his execution.

A young boy uses his scientific skills to fight enemies.

Dr. Slump creates a little android girl, Arale, who is very stong, happy, and totally common senseless. They live in Penguin Village where the strangest things happen (e.g., the dawn is announced by a little pig wearing a basquee). (Source: ANN)

Megu is sent to Earth in her early teens, she is adopted by Mammi Kanzaki, a former witch who gave up her royal ambitions to wed a mortal. Mammi bewitches her husband and their two children, Rabi and Apo, into believing that Megu has always been the eldest child of the family. Under Mammi's tutelage, Megu learns to control both her abilities and impulses in order to prove her worthiness for the crown. This Rite-of-Passage subtext is continued throughout the series.