It is common knowledge that nobles will do anything for power; lying, manipulation, and extortion are the usual tactics. However, one family is exempt from this generalization: House Grail, whose main tenets are truth and integrity. The youngest daughter, Constance Grail, is just as moral as the rest of her family, believing in always doing the right thing and helping those in need. However, these ideals do not help her when her fiancé cheats on her with another woman. Framed by his lover in the hope of her downfall, Constance's pleas for justice are ignored. Everyone turns a blind eye, save for one—the spirit of the infamous Scarlet Castiel—who possesses Constance and turns the tables on her accuser. However, this aid doesn't come without a price. Ten years ago, Scarlet was executed for the attempted murder of Princess Cecilia. But this was actually a setup; as blunt and harsh as Scarlet could be, she would never stoop so low as to use poison. She has no idea who orchestrated her incrimination, but Scarlet demands that Constance—as the only one who can see her—help her exact revenge on all those who wronged her!

For as long as the locals can remember, the Champignon Witch, Luna, has lived hidden in her cottage on the outskirts of the kingdom, deep within the Black Forest. Despite her occasional trips into town to deliver medicine, no one dares to come close to her as poisonous mushrooms grow everywhere she goes. Furthermore, as a black witch, Luna must lay low to avoid execution, as the kingdom only acknowledges and accepts white witches. Luna's lonely life turns around when she saves a dying boy named Lize. Upon learning that Lize is destined to become The End of All Things, Luna offers to become his teacher and stray him away from the path of evil. She must overcome her inexperience and create a great magician out of Lize to avoid his execution.

Saku Chitose appears to lead an enviable high school life. Extraordinarily charismatic, tremendously confident, and effortlessly friendly, he is the kind of person others naturally look up to. But his popularity carries its own burdens; not everyone views him kindly, and whispers of cynicism follow wherever he shines too brightly. To Saku, living an ugly life is worse than death—a belief that drives his need to maintain his perfect reputation. At the start of his second year, Saku's homeroom teacher asks him to help bring back a classmate who has stopped attending school. Initially hoping to resolve the matter quickly, Saku finds out that the shut-in Kenta Yamazaki harbors open contempt for him and everything he represents. A simple favor instead exposes the distance between those who live within the social light and those who were never given a chance to shine. Surrounded by the expectant gazes of those who both admire and despise him, Saku treads the delicate line between sincerity and performance—searching for what it truly means to live beautifully in a world that sees only the surface.

Atsuko "Akko-chan" Kagami (known variously as "Stilly," "Caroline," or "Julie" in Western versions of the anime) is an energetic elementary school girl who has an affinity for mirrors. One day, her favorite mirror which was given to Akko by her mother (or in some versions, by her father, as a present from India) is broken, and she prefers to bury it in her yard rather than throw it to the trash can. In her dreams, she is contacted by a spirit (or in some cases the Queen of the Mirror Kingdom) who is moved that the little girl would treat the mirror so respectfully and not simply throw it away. Akko-chan is then given the gift of a magical mirror and taught an enchantment that will allow her to transform into anything she wishes.